Search Resources (English): Adverse drug effect

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Canada's adverse drug reaction database

Provides a searchable database that holds information from all adverse drug reaction (ADR) reports currently held in Health Canada's CADRIS (Canadian Adverse Drug Reaction Information System) database, which monitors adverse drug reactions in drugs approved for the Canadian market.

Published: 1965-2004
Canadian adverse reaction newsletter

Provides a newsletter that contains adverse reaction information and is published quarterly, in January, April, July and October of each year. Alerts health professionals to potential signals detected through the review of case reports submitted to Health Canada, and also disseminates information on suspected adverse reactions to health products occurring in humans before comprehensive risk-benefit evaluations and regulatory decisions are undertaken.

Important safety concerns on the use of Diane-35  
http://www.hc-sc.gc.ca/dhp-mps/alt_formats/hpfb-dgpsa/pdf/medeff/diane-35_hpc-cps-eng.pdf

Discusses an article regarding important safety concerns on the use of cyproterone acetate (marketed as Diane-35 in Canada, and as Dianette in the United Kingdom).

 (See Details)
Published: 2002
A hard pill to swallow  
http://www.cbc.ca/consumers/market/files/health/diane/index.html#
Examines the health risks associated with Diane-35, a drug to treat severe acne, yet marketed as a bill control pill. (See Details)
Published: 2005
Reporting harm caused by medicines  
http://www.whp-apsf.ca/en/documents/adrReport.html
Discusses why women should report all cases of known or suspected harm from prescription drugs and medicines. Provides contact information for consumers who wish to file a report. (See Details)
Published: 2005
Post-market surveillance of therapeutic drugs in Canada  
http://www.whp-apsf.ca/en/documents/adrBackground.html
Discusses the importance of an effective post-market surveillance system of therapeutic drugs. Lists problems with the current system, and argues that improvements will only occur when there is greater consumer involvement. (See Details)
Published: 2005
The Evra (ethinyl estradiol/norelgestromin) contraceptive patch: estrogen exposure concerns  
http://www.cmaj.ca/cgi/content/full/174/2/164
Reviews the Evra patch and the potential for excess estrogen exposure raises concerns about the risks of adverse effects, which include nausea, breast tenderness and venous thromboembolism. (See Details)
Published: 2006
Diane-35 (cyproterone acetate): safety concerns  
http://www.cmaj.ca/cgi/content/full/168/4/455
Discusses warnings regarding the drug, Diane-35, and the drug's risk of venous thromboembolism. States that Diane-35 should be reserved for temporary use in women with serious acne and should not be used solely as an oral contraceptive. (See Details)
Published: 2003
Newly developed drugs pose more dangers for patients  
http://www.cwhn.ca/resources/afi/drugs.html
Explains that unexpected serious reactions often turn up after a drug appears on the market and that it can take years of use before doctors discover serious drug toxicity. (See Details)
Published: 2003
Keeping tabs on drug reactions  
http://www.cwhn.ca/resources/drugs/reactions.html
Explains why PharmaWatch and Women and Health Protection are calling on Health Canada to establish a more effective system for reporting and monitoring adverse drug reactions. (See Details)
Published: 2004