Set of six articles, written from an American perspective, introducing the issue of women’s exclusion from clinical drug trials. Examines how and why women have historically been under-represented in or excluded from drug trials, and the negative effects this has had on women’s health care. Asks whether women have yet achieved adequate access to clinical research. (Requires free registration in Medscape to access.)
Provides a plain language overview of the clinical trial process and the different kinds of trials for those interested in participating in clinical trials, as well as anyone wanting to learn how they are conducted.
Looks at the ethical questions surrounding microbicide research, particularly care issues for people in resource-poor countries who sero-convert during clinical trials.
Addresses the issues evoked in considering the inclusion of women in clinical trials, highlighting especially where gender, even more than sex, is pertinent.
Discusses the use of cholinesterase inhibitors in patients with a variety of types of dementia and cognitive impairment, looking critically at the clinical trial evidence on these drugs.
Reviews women's concerns about enrolling in HIV vaccine trials, fears of adverse events, issues of informed consent, barriers faced by sex workers, benefits of participation, and the role of researchers as human rights advocates.
Promotes the development of treatments, vaccines and a cure for HIV/AIDS through the conduct of scientifically sound and ethical clinical trials. Website provides information about clinical trials in Canada, including a clinical trials database.
Evaluates the safety and efficacy of raloxifene compared with placebo and other drugs approved in Canada for the primary and secondary prevention of osteoporotic vertebral fractures in postmenopausal women.
Describes microbicides, substances that would reduce the transmission of sexually transmitted infections (STIs) when used vaginally or rectally. Summarizes extensive deliberations, key decisions and recommendations made at a 1997 symposium of 55 advocates, scientists, policy makers, and industry representatives from 15 countries across Africa, Asia, Latin America, Europe, and the United States. Addresses such complex issues as informed consent, standard of care, community participation, the role of social science, and implications for public policy.
